Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with Target = 'Alpha-2A/Alpha-2B/Alpha-2C adrenergic receptor' and Ligand = 'BDBM34572'
TargetAlpha-2A/Alpha-2B/Alpha-2C adrenergic receptor(Human)
University of Dublin

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 34572BDBM34572(UK 14,304 | SMR000058355 | CHEMBL844 | cid_2435 | ...)
Affinity DataKi:  1.40nMAssay Description:Binding affinity to alpha2 adrenoceptor in human cortical membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAlpha-2A/Alpha-2B/Alpha-2C adrenergic receptor(Human)
University of Dublin

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 34572BDBM34572(UK 14,304 | SMR000058355 | CHEMBL844 | cid_2435 | ...)
Affinity DataKi:  2.40nMAssay Description:Binding affinity towards Alpha-2 adrenergic receptor of HT-29 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2018
Entry Details
PDB3D3D Structure (crystal)
TargetAlpha-2A/Alpha-2B/Alpha-2C adrenergic receptor(Human)
University of Dublin

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 34572BDBM34572(UK 14,304 | SMR000058355 | CHEMBL844 | cid_2435 | ...)
Affinity DataKi:  2.40nMAssay Description:Binding affinity for Alpha-2 adrenergic receptor of CHO-C10 membrane preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2018
Entry Details
PDB3D3D Structure (crystal)
TargetAlpha-2A/Alpha-2B/Alpha-2C adrenergic receptor(Human)
University of Dublin

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 34572BDBM34572(UK 14,304 | SMR000058355 | CHEMBL844 | cid_2435 | ...)
Affinity DataIC50: 3nMAssay Description:Inhibition of [3H]p-aminoclonidine (PAC) binding to alpha-2 adrenergic receptor of purified human platelet plasma membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2018
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAlpha-2A/Alpha-2B/Alpha-2C adrenergic receptor(Human)
University of Dublin

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 34572BDBM34572(UK 14,304 | SMR000058355 | CHEMBL844 | cid_2435 | ...)
Affinity DataEC50:  1.14E+4nMAssay Description:Agonist activity at alpha2 adrenoceptor in human cortical membrane after 2 hrs by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAlpha-2A/Alpha-2B/Alpha-2C adrenergic receptor(Human)
University of Dublin

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 34572BDBM34572(UK 14,304 | SMR000058355 | CHEMBL844 | cid_2435 | ...)
Affinity DataEC50:  1.14E+4nMAssay Description:Agonist activity at human brain adrenergic alpha2 receptor by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)