Found 6 Enz. Inhib. hit(s) with Target = 'Alpha-2A/Alpha-2B/Alpha-2C adrenergic receptor' and Ligand = 'BDBM34572' TargetAlpha-2A/Alpha-2B/Alpha-2C adrenergic receptor(Homo sapiens (Human))
University Of Dublin
Curated by ChEMBL
University Of Dublin
Curated by ChEMBL
Affinity DataKi: 1.40nMAssay Description:Binding affinity to alpha2 adrenoceptor in human cortical membraneMore data for this Ligand-Target Pair
3D Structure (crystal)TargetAlpha-2A/Alpha-2B/Alpha-2C adrenergic receptor(Homo sapiens (Human))
University Of Dublin
Curated by ChEMBL
University Of Dublin
Curated by ChEMBL
Affinity DataKi: 2.40nMAssay Description:Binding affinity towards Alpha-2 adrenergic receptor of HT-29 cellsMore data for this Ligand-Target Pair
TargetAlpha-2A/Alpha-2B/Alpha-2C adrenergic receptor(Homo sapiens (Human))
University Of Dublin
Curated by ChEMBL
University Of Dublin
Curated by ChEMBL
Affinity DataKi: 2.40nMAssay Description:Binding affinity for Alpha-2 adrenergic receptor of CHO-C10 membrane preparationMore data for this Ligand-Target Pair
TargetAlpha-2A/Alpha-2B/Alpha-2C adrenergic receptor(Homo sapiens (Human))
University Of Dublin
Curated by ChEMBL
University Of Dublin
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of [3H]p-aminoclonidine (PAC) binding to alpha-2 adrenergic receptor of purified human platelet plasma membranesMore data for this Ligand-Target Pair
TargetAlpha-2A/Alpha-2B/Alpha-2C adrenergic receptor(Homo sapiens (Human))
University Of Dublin
Curated by ChEMBL
University Of Dublin
Curated by ChEMBL
Affinity DataEC50: 1.14E+4nMAssay Description:Agonist activity at human brain adrenergic alpha2 receptor by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
TargetAlpha-2A/Alpha-2B/Alpha-2C adrenergic receptor(Homo sapiens (Human))
University Of Dublin
Curated by ChEMBL
University Of Dublin
Curated by ChEMBL
Affinity DataEC50: 1.14E+4nMAssay Description:Agonist activity at alpha2 adrenoceptor in human cortical membrane after 2 hrs by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
