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Found 3 Enz. Inhib. hit(s) with Target = 'Alpha-ketoglutarate-dependent dioxygenase FTO' and Ligand = 'BDBM50596053'
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Homo sapiens (Human))TBA
LigandPNGBDBM50596053(CHEMBL5173876)
Affinity DataIC50:  810nMAssay Description:Inhibition of human full length FTO expressed in Escherichia coli BL21 (DE3) Rosetta T1R cells using 3-methylthymidine as substrate incubated for 1 h...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Homo sapiens (Human))TBA
LigandPNGBDBM50596053(CHEMBL5173876)
Affinity DataIC50:  930nMAssay Description:Inhibition of FTO (unknown origin) demethylation activity by HPLC assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Homo sapiens (Human))TBA
LigandPNGBDBM50596053(CHEMBL5173876)
Affinity DataIC50:  1.25E+4nMAssay Description:Inhibition of recombinant full length N-terminal hexahistidine-tagged human FTO demethylation activity expressed in Escherichia coli BL21 (DE3) incub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB