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Found 1 Enz. Inhib. hit(s) with Target = 'Amyloid-beta precursor protein [672-711]' and Ligand = 'BDBM50129276'
TargetAmyloid-beta precursor protein [672-711](Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50129276(CHEMBL3629737 | US9464103, (6aR,10aS)-10a-(4-chlor...)
Affinity DataIC50:  66.6nMpH: 7.0Assay Description:To measure γ-secretase activity, membranes were incubated at 37° C. for 1 h in 50 μL of buffer containing 20 mM Hepes (pH 7.0) and 2 mM EDT...More data for this Ligand-Target Pair
In DepthDetails US Patent