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Found 3 Enz. Inhib. hit(s) with Target = 'Androgen receptor' and Ligand = 'BDBM50317652'
TargetAndrogen receptor(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50317652(4-[3-(4-Cyano-3-trifluoromethylphenyl)-5,5-dimethy...)
Affinity DataIC50:  55nMAssay Description:Antagonist activity at AR in bicalutamide-resistant human LNCAP cells assessed as effect on cell proliferation after 6 daysMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50317652(4-[3-(4-Cyano-3-trifluoromethylphenyl)-5,5-dimethy...)
Affinity DataIC50:  400nMAssay Description:Antagonist activity at AR in human LNCAP cells assessed as effect on cell proliferation after 6 daysMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50317652(4-[3-(4-Cyano-3-trifluoromethylphenyl)-5,5-dimethy...)
Affinity DataIC50:  480nMAssay Description:Displacement of [3H]mibolerone from human AR expressed in CHO-K1 cells after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed