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Found 3 Enz. Inhib. hit(s) with Target = 'Anoctamin-1' and Ligand = 'BDBM50503445'
TargetAnoctamin-1(Homo sapiens (Human))
Yonsei University

Curated by ChEMBL
LigandPNGBDBM50503445(CHEMBL4445544 | US11274074, Example 1 [Chemical Fo...)
Affinity DataIC50:  21nMAssay Description:Inhibition of YFP-fused ANO1 (unknown origin) expressed in FRT cells after 20 mins by fluorescence quenching methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAnoctamin-1(Homo sapiens (Human))
Yonsei University

Curated by ChEMBL
LigandPNGBDBM50503445(CHEMBL4445544 | US11274074, Example 1 [Chemical Fo...)
Affinity DataIC50:  21nMAssay Description:The method for inhibiting the expression of ANO1 (TMEM16A) of the present disclosure includes a step of inhibiting the expression of ANO1 (TMEM16A) i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAnoctamin-1(Homo sapiens (Human))
Yonsei University

Curated by ChEMBL
LigandPNGBDBM50503445(CHEMBL4445544 | US11274074, Example 1 [Chemical Fo...)
Affinity DataIC50:  22nMAssay Description:Inhibition of ANO1 (unknown origin) expressed in FRT cells assessed as reduction in ATP-induced chloride current after 20 mins by electrophysiologica...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed