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Found 9 Enz. Inhib. hit(s) with Target = 'Apelin receptor' and Ligand = 'BDBM270010'
TargetApelin receptor(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM270010((1S,2R)-1-(5-chloro-2-pyrimidinyl)-N-(4-(2,6-dimet...)
Affinity DataEC50:  0.310nMpH: 7.5Assay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV¿-3 expression vector (Si...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApelin receptor(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM270010((1S,2R)-1-(5-chloro-2-pyrimidinyl)-N-(4-(2,6-dimet...)
Affinity DataEC50:  30nMpH: 7.5Assay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV¿-3 expression vector (Si...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApelin receptor(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM270010((1S,2R)-1-(5-chloro-2-pyrimidinyl)-N-(4-(2,6-dimet...)
Affinity DataEC50:  120nMpH: 7.5Assay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV¿-3 expression vector (Si...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApelin receptor(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM270010((1S,2R)-1-(5-chloro-2-pyrimidinyl)-N-(4-(2,6-dimet...)
Affinity DataEC50:  0.880nMpH: 7.5Assay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV¿-3 expression vector (Si...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApelin receptor(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM270010((1S,2R)-1-(5-chloro-2-pyrimidinyl)-N-(4-(2,6-dimet...)
Affinity DataEC50:  0.880nMAssay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV™-3 expression vector (Si...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApelin receptor(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM270010((1S,2R)-1-(5-chloro-2-pyrimidinyl)-N-(4-(2,6-dimet...)
Affinity DataEC50:  0.310nMAssay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV™-3 expression vector (Si...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApelin receptor(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM270010((1S,2R)-1-(5-chloro-2-pyrimidinyl)-N-(4-(2,6-dimet...)
Affinity DataEC50:  30nMAssay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV™-3 expression vector (Si...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApelin receptor(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM270010((1S,2R)-1-(5-chloro-2-pyrimidinyl)-N-(4-(2,6-dimet...)
Affinity DataEC50:  120nMAssay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV™-3 expression vector (Si...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApelin receptor(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM270010((1S,2R)-1-(5-chloro-2-pyrimidinyl)-N-(4-(2,6-dimet...)
Affinity DataEC50:  2.5nMAssay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV™-3 expression vector (Si...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent