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Found 2 Enz. Inhib. hit(s) with Target = 'Apoptosis regulator BAX' and Ligand = 'BDBM50078015'
TargetApoptosis regulator BAX(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50078015(CHEMBL3417395)
Affinity DataKi:  1.10E+3nMAssay Description:Displacement of FITC-BIM from recombinant N-terminal GST-tagged human BAX expressed in Escherichia coli after 30 mins by fluorescence polarization as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator BAX(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50078015(CHEMBL3417395)
Affinity DataEC50:  8.20E+3nMAssay Description:Activation of Bax in human HuH7 cells assessed as inhibition of mitochondrial accumulation of fluorescent probe Mitotracker Red after 12 to 72 hrs by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed