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Found 5 Enz. Inhib. hit(s) with Target = 'Ataxin-2' and Ligand = 'BDBM442718'
TargetAtaxin-2(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM442718(US10647719, Example 2.00 | US10647719, Example 2.0...)
Affinity DataIC50:  1.90nMAssay Description:Human carbonic anhydrase II (hCA-II) inhibition was measured by an absorbance method using 4-nitrophenyl acetate (4-NPA) as its substrate. 4-NPA can ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAtaxin-2(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM442718(US10647719, Example 2.00 | US10647719, Example 2.0...)
Affinity DataIC50:  6nMAssay Description:Human carbonic anhydrase II (hCA-II) inhibition was measured by an absorbance method using 4-nitrophenyl acetate (4-NPA) as its substrate. 4-NPA can ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAtaxin-2(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM442718(US10647719, Example 2.00 | US10647719, Example 2.0...)
Affinity DataIC50:  8nMAssay Description:Human carbonic anhydrase II (hCA-II) inhibition was measured by an absorbance method using 4-nitrophenyl acetate (4-NPA) as its substrate. 4-NPA can ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAtaxin-2(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM442718(US10647719, Example 2.00 | US10647719, Example 2.0...)
Affinity DataIC50:  18nMAssay Description:Human carbonic anhydrase II (hCA-II) inhibition was measured by an absorbance method using 4-nitrophenyl acetate (4-NPA) as its substrate. 4-NPA can ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAtaxin-2(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM442718(US10647719, Example 2.00 | US10647719, Example 2.0...)
Affinity DataIC50:  24nMAssay Description:Human carbonic anhydrase II (hCA-II) inhibition was measured by an absorbance method using 4-nitrophenyl acetate (4-NPA) as its substrate. 4-NPA can ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent