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Found 2 Enz. Inhib. hit(s) with Target = 'Aurora kinase A' and Ligand = 'BDBM50453822'
TargetAurora kinase A(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50453822(CHEMBL3969370)
Affinity DataIC50:  44nMAssay Description:Inhibition of recombinant full length His-tagged human Aurora A expressed in baculovirus expression system by Z'LYTE assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50453822(CHEMBL3969370)
Affinity DataEC50:  5.80nMAssay Description:Inhibition of Aurora A auto-phosphorylation in human HCT116 cells after 4 hrs by Western blot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed