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Found 7 Enz. Inhib. hit(s) with Target = 'B1 bradykinin receptor' and Ligand = 'BDBM50156446'
TargetB1 bradykinin receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50156446(CHEMBL359553 | N-{2-[4-(4,5-Dihydro-1H-imidazol-2-...)
Affinity DataKi:  0.0200nMAssay Description:Binding affinity of the [35S]- radiolabelled compound to human Bradykinin receptor B1 over-expressed in transgenic rats was determined by ex vivo rec...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50156446(CHEMBL359553 | N-{2-[4-(4,5-Dihydro-1H-imidazol-2-...)
Affinity DataKi:  0.0200nMAssay Description:Binding affinity of the [35S]- radiolabelled compound to rhesus monkey Bradykinin receptor B1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB1 bradykinin receptor(Oryctolagus cuniculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50156446(CHEMBL359553 | N-{2-[4-(4,5-Dihydro-1H-imidazol-2-...)
Affinity DataKi:  0.0500nMAssay Description:Binding affinity of the [35S]- radiolabelled compound to rabbit Bradykinin receptor B1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB1 bradykinin receptor(Canis familiaris)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50156446(CHEMBL359553 | N-{2-[4-(4,5-Dihydro-1H-imidazol-2-...)
Affinity DataKi:  0.5nMAssay Description:Binding affinity of the [35S]- radiolabelled compound to dog Bradykinin receptor B1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB1 bradykinin receptor(RAT)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50156446(CHEMBL359553 | N-{2-[4-(4,5-Dihydro-1H-imidazol-2-...)
Affinity DataKi:  34nMAssay Description:Binding affinity of the [35S]- radiolabelled compound to rat Bradykinin receptor B1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50156446(CHEMBL359553 | N-{2-[4-(4,5-Dihydro-1H-imidazol-2-...)
Affinity DataIC50:  0.0400nMAssay Description:Antagonist activity of the compound against human Bradykinin receptor B1 was determined in a fluorescence imaging plate reader assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50156446(CHEMBL359553 | N-{2-[4-(4,5-Dihydro-1H-imidazol-2-...)
Affinity DataKd:  0.0150nMAssay Description:Equilibrium dissociation constant of the [35S]- radiolabelled compound against human Bradykinin receptor B1 expressed in CHO membranes was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed