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Found 18 Enz. Inhib. hit(s) with Target = 'BDNF/NT-3 growth factors receptor' and Ligand = 'BDBM136597'
TargetBDNF/NT-3 growth factors receptor(Homo sapiens (Human))
Shenzhen Targetrx

US Patent
LigandPNGBDBM136597(US10005783, 14 | US10047097, 14 | US10774085, Exam...)
Affinity DataIC50:  0.330nMAssay Description:Kinase assay: After the buffer was prepared, the enzyme was mixed with different concentrations of the compound prepared by pre-diluting, and allowed...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBDNF/NT-3 growth factors receptor(Homo sapiens (Human))
Shenzhen Targetrx

US Patent
LigandPNGBDBM136597(US10005783, 14 | US10047097, 14 | US10774085, Exam...)
Affinity DataIC50:  0.400nMAssay Description:Kinase assay: After the buffer was prepared, the enzyme was mixed with different concentrations of the compound prepared by pre-diluting, and allowed...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBDNF/NT-3 growth factors receptor(Homo sapiens (Human))
Shenzhen Targetrx

US Patent
LigandPNGBDBM136597(US10005783, 14 | US10047097, 14 | US10774085, Exam...)
Affinity DataIC50:  0.460nMAssay Description:Kinase assay: After the buffer was prepared, the enzyme was mixed with different concentrations of the compound prepared by pre-diluting, and allowed...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBDNF/NT-3 growth factors receptor(Homo sapiens (Human))
Shenzhen Targetrx

US Patent
LigandPNGBDBM136597(US10005783, 14 | US10047097, 14 | US10774085, Exam...)
Affinity DataIC50:  0.460nMAssay Description:Kinase assay: After the buffer was prepared, the enzyme was mixed with different concentrations of the compound prepared by pre-diluting, and allowed...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBDNF/NT-3 growth factors receptor(Homo sapiens (Human))
Shenzhen Targetrx

US Patent
LigandPNGBDBM136597(US10005783, 14 | US10047097, 14 | US10774085, Exam...)
Affinity DataIC50:  0.540nMAssay Description:Kinase assay: After the buffer was prepared, the enzyme was mixed with different concentrations of the compound prepared by pre-diluting, and allowed...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBDNF/NT-3 growth factors receptor(Homo sapiens (Human))
Shenzhen Targetrx

US Patent
LigandPNGBDBM136597(US10005783, 14 | US10047097, 14 | US10774085, Exam...)
Affinity DataIC50:  0.630nMAssay Description:Kinase assay: After the buffer was prepared, the enzyme was mixed with different concentrations of the compound prepared by pre-diluting, and allowed...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBDNF/NT-3 growth factors receptor(Homo sapiens (Human))
Shenzhen Targetrx

US Patent
LigandPNGBDBM136597(US10005783, 14 | US10047097, 14 | US10774085, Exam...)
Affinity DataIC50:  2.10nMAssay Description:Inhibition of Trk-B (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBDNF/NT-3 growth factors receptor(Homo sapiens (Human))
Shenzhen Targetrx

US Patent
LigandPNGBDBM136597(US10005783, 14 | US10047097, 14 | US10774085, Exam...)
Affinity DataIC50:  2.30nMAssay Description:Inhibition of TrkB (unknown origin) using Tyr1 peptide as substrate in presence of ATP measured after 2 hrs by FRET-based Z-Lyte kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBDNF/NT-3 growth factors receptor(Homo sapiens (Human))
Shenzhen Targetrx

US Patent
LigandPNGBDBM136597(US10005783, 14 | US10047097, 14 | US10774085, Exam...)
Affinity DataIC50:  3.20nMAssay Description:Inhibition of TRKB (unknown origin) in presence of [gamma33P]ATP by radiometric HotSpot assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetBDNF/NT-3 growth factors receptor(Homo sapiens (Human))
Shenzhen Targetrx

US Patent
LigandPNGBDBM136597(US10005783, 14 | US10047097, 14 | US10774085, Exam...)
Affinity DataIC50:  3.30nMAssay Description:Inhibition of TRKB (unknown origin) incubated for 40 mins in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetBDNF/NT-3 growth factors receptor(Homo sapiens (Human))
Shenzhen Targetrx

US Patent
LigandPNGBDBM136597(US10005783, 14 | US10047097, 14 | US10774085, Exam...)
Affinity DataIC50:  5nMAssay Description:Inhibition of TrkB (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetBDNF/NT-3 growth factors receptor(Homo sapiens (Human))
Shenzhen Targetrx

US Patent
LigandPNGBDBM136597(US10005783, 14 | US10047097, 14 | US10774085, Exam...)
Affinity DataIC50:  5nMAssay Description:Inhibition of TrkB (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBDNF/NT-3 growth factors receptor(Homo sapiens (Human))
Shenzhen Targetrx

US Patent
LigandPNGBDBM136597(US10005783, 14 | US10047097, 14 | US10774085, Exam...)
Affinity DataIC50:  5nMAssay Description:Inhibition of wild type TRKB (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBDNF/NT-3 growth factors receptor(Homo sapiens (Human))
Shenzhen Targetrx

US Patent
LigandPNGBDBM136597(US10005783, 14 | US10047097, 14 | US10774085, Exam...)
Affinity DataIC50:  5nMAssay Description:Inhibition of TRKB (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetBDNF/NT-3 growth factors receptor(Homo sapiens (Human))
Shenzhen Targetrx

US Patent
LigandPNGBDBM136597(US10005783, 14 | US10047097, 14 | US10774085, Exam...)
Affinity DataIC50:  5.20nMAssay Description:Inhibition of recombinant human His-tagged TrkB catalytic domain (526 to 838 residues) expressed in baculovirus expression system using tyr 01 as sub...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBDNF/NT-3 growth factors receptor(Homo sapiens (Human))
Shenzhen Targetrx

US Patent
LigandPNGBDBM136597(US10005783, 14 | US10047097, 14 | US10774085, Exam...)
Affinity DataIC50:  8.10nMAssay Description:Inhibition of TRKB (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetBDNF/NT-3 growth factors receptor(Homo sapiens (Human))
Shenzhen Targetrx

US Patent
LigandPNGBDBM136597(US10005783, 14 | US10047097, 14 | US10774085, Exam...)
Affinity DataIC50:  13nMAssay Description:Inhibition of TRKB (unknown origin) using TK as substrate in presence of ATP incubated for 40 mins by HTRF KinEASE assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetBDNF/NT-3 growth factors receptor(Homo sapiens (Human))
Shenzhen Targetrx

US Patent
LigandPNGBDBM136597(US10005783, 14 | US10047097, 14 | US10774085, Exam...)
Affinity DataIC50:  24nMAssay Description:Inhibition of TrkB (unknown origin) by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed