Report error Found 23 Enz. Inhib. hit(s) with Target = 'Bcl-2-like protein 1' and Ligand = 'BDBM21447'
Affinity DataKi: 0.0800nMAssay Description:The inhibition constant (Ki) is the dissociation constant of an enzyme-inhibitor complex or a protein/small molecule complex, wherein the small molec...More data for this Ligand-Target Pair
TargetBcl-2-like protein 1(Human)
The Walter and Eliza Hall Institute of Medical Research
Curated by ChEMBL
The Walter and Eliza Hall Institute of Medical Research
Curated by ChEMBL
Affinity DataKd: 0.130nMAssay Description:Binding affinity to human GST-tagged Bcl-Xl assessed as dissociation rate by surface plasmon resonance assayMore data for this Ligand-Target Pair
TargetBcl-2-like protein 1(Human)
The Walter and Eliza Hall Institute of Medical Research
Curated by ChEMBL
The Walter and Eliza Hall Institute of Medical Research
Curated by ChEMBL
Affinity DataKd: 0.370nMAssay Description:Binding affinity to Bcl-XlMore data for this Ligand-Target Pair
TargetBcl-2-like protein 1(Human)
The Walter and Eliza Hall Institute of Medical Research
Curated by ChEMBL
The Walter and Eliza Hall Institute of Medical Research
Curated by ChEMBL
Affinity DataKi: <0.5nMAssay Description:Binding affinity to Bcl-xL (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
TargetBcl-2-like protein 1(Human)
The Walter and Eliza Hall Institute of Medical Research
Curated by ChEMBL
The Walter and Eliza Hall Institute of Medical Research
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Binding affinity to human GST-tagged Bcl-Xl by luminescence proximity assayMore data for this Ligand-Target Pair
TargetBcl-2-like protein 1(Human)
The Walter and Eliza Hall Institute of Medical Research
Curated by ChEMBL
The Walter and Eliza Hall Institute of Medical Research
Curated by ChEMBL
Affinity DataKi: <0.5nM IC50: 60nM EC50: 30nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
TargetBcl-2-like protein 1(Human)
The Walter and Eliza Hall Institute of Medical Research
Curated by ChEMBL
The Walter and Eliza Hall Institute of Medical Research
Curated by ChEMBL
Affinity DataKi: 1nMAssay Description:Inhibition of 5-FAM-Bid peptide binding to Bcl-XL (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetBcl-2-like protein 1(Human)
The Walter and Eliza Hall Institute of Medical Research
Curated by ChEMBL
The Walter and Eliza Hall Institute of Medical Research
Curated by ChEMBL
Affinity DataKi: <1nMAssay Description:Inhibition of Bcl-xL (unknown origin)More data for this Ligand-Target Pair
TargetBcl-2-like protein 1(Human)
The Walter and Eliza Hall Institute of Medical Research
Curated by ChEMBL
The Walter and Eliza Hall Institute of Medical Research
Curated by ChEMBL
Affinity DataKi: <1nMAssay Description:Displacement of fluorescein-labeled BAK from His-tagged BCL-XL (unknown origin) after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetBcl-2-like protein 1(Human)
The Walter and Eliza Hall Institute of Medical Research
Curated by ChEMBL
The Walter and Eliza Hall Institute of Medical Research
Curated by ChEMBL
Affinity DataKi: <1nMAssay Description:Inhibition of Bcl-xL (unknown origin)More data for this Ligand-Target Pair
TargetBcl-2-like protein 1(Human)
The Walter and Eliza Hall Institute of Medical Research
Curated by ChEMBL
The Walter and Eliza Hall Institute of Medical Research
Curated by ChEMBL
TargetBcl-2-like protein 1(Human)
The Walter and Eliza Hall Institute of Medical Research
Curated by ChEMBL
The Walter and Eliza Hall Institute of Medical Research
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Displacement of biotinylated Bim-BH3 from GST-tagged Bcl-Xl by AlphaScreen competitive assayMore data for this Ligand-Target Pair
TargetBcl-2-like protein 1(Human)
The Walter and Eliza Hall Institute of Medical Research
Curated by ChEMBL
The Walter and Eliza Hall Institute of Medical Research
Curated by ChEMBL
Affinity DataKi: 3.40nMAssay Description:Displacement of BODIPY-Bak conjugated peptide from GST-tagged human Wild type Bcl-2-like protein 1 expressed in Escherichia coli BL21 cells at 10 uM ...More data for this Ligand-Target Pair
TargetBcl-2-like protein 1(Human)
The Walter and Eliza Hall Institute of Medical Research
Curated by ChEMBL
The Walter and Eliza Hall Institute of Medical Research
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Binding affinity to N-terminus 8X His-tagged human Bcl-xL expressed in Escherichia coli BL21 (DE3) cells after 2 hrs by fluorescence polarization ass...More data for this Ligand-Target Pair
TargetBcl-2-like protein 1(Human)
The Walter and Eliza Hall Institute of Medical Research
Curated by ChEMBL
The Walter and Eliza Hall Institute of Medical Research
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition of GST-tagged Bcl-xL (unknown origin) measured after 1 hr incubation by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetBcl-2-like protein 1(Human)
The Walter and Eliza Hall Institute of Medical Research
Curated by ChEMBL
The Walter and Eliza Hall Institute of Medical Research
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition of human N-terminal His8-tagged Bcl-XL expressed in Escherichia coli BL21(DE3) assessed as inhibition of Fluorescein-labeled BAK binding a...More data for this Ligand-Target Pair
TargetBcl-2-like protein 1(Human)
The Walter and Eliza Hall Institute of Medical Research
Curated by ChEMBL
The Walter and Eliza Hall Institute of Medical Research
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Binding affinity to human GST-tagged Bcl-Xl by surface plasmon resonance assayMore data for this Ligand-Target Pair
TargetBcl-2-like protein 1(Human)
The Walter and Eliza Hall Institute of Medical Research
Curated by ChEMBL
The Walter and Eliza Hall Institute of Medical Research
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of Bcl-xL (unknown origin) by surface plasmon resonance assayMore data for this Ligand-Target Pair
TargetBcl-2-like protein 1(Human)
The Walter and Eliza Hall Institute of Medical Research
Curated by ChEMBL
The Walter and Eliza Hall Institute of Medical Research
Curated by ChEMBL
Affinity DataEC50: 30.0nMAssay Description:Inhibition of Bcl-XLMore data for this Ligand-Target Pair
TargetBcl-2-like protein 1(Human)
The Walter and Eliza Hall Institute of Medical Research
Curated by ChEMBL
The Walter and Eliza Hall Institute of Medical Research
Curated by ChEMBL
Affinity DataKi: 30nMAssay Description:Binding affinity to Bcl-xlMore data for this Ligand-Target Pair
TargetBcl-2-like protein 1(Human)
The Walter and Eliza Hall Institute of Medical Research
Curated by ChEMBL
The Walter and Eliza Hall Institute of Medical Research
Curated by ChEMBL
Affinity DataKi: <40nMAssay Description:Inhibition of BCL-xL (unknown origin) by fluorescence polarization competition assayMore data for this Ligand-Target Pair
TargetBcl-2-like protein 1(Human)
The Walter and Eliza Hall Institute of Medical Research
Curated by ChEMBL
The Walter and Eliza Hall Institute of Medical Research
Curated by ChEMBL
Affinity DataKi: 188nMAssay Description:Inhibition of recombinant His6-tagged Bcl-XL expressed in Escherichia coli BL21 (DE3) and Flu-Bak peptide interaction by fluorescence polarization as...More data for this Ligand-Target Pair
TargetBcl-2-like protein 1(Human)
The Walter and Eliza Hall Institute of Medical Research
Curated by ChEMBL
The Walter and Eliza Hall Institute of Medical Research
Curated by ChEMBL
Affinity DataKi: 284nMAssay Description:Inhibition of Bcl-xL (unknown origin)More data for this Ligand-Target Pair
