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Found 6 Enz. Inhib. hit(s) with Target = 'Beta-1 adrenergic receptor' and Ligand = 'BDBM50407517'
TargetBeta-1 adrenergic receptor(Mus musculus)
Friedrich-Alexander University Erlangen-N£Rnberg (Fau)

Curated by ChEMBL
LigandPNGBDBM50407517((-)ISOPROTERENOL | CHEMBL1160723 | US9492405, 27)
Affinity DataKi:  220nMAssay Description:Displacement of [3H]-CGP-12177 from murine beta1-adrenergic receptor expressed in HEK293T cells after 60 mins by radioligand competition binding assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1 adrenergic receptor(Homo sapiens (Human))
Friedrich-Alexander University Erlangen-N£Rnberg (Fau)

Curated by ChEMBL
LigandPNGBDBM50407517((-)ISOPROTERENOL | CHEMBL1160723 | US9492405, 27)
Affinity DataEC50:  25nMAssay Description:Agonist activity at beta1-adrenergic receptor (unknown origin) expressed in HEK293T cells harboring Rluc2-117-GalphaS/GFP10-Ggamma/Gbeta1 assessed as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1 adrenergic receptor(Homo sapiens (Human))
Friedrich-Alexander University Erlangen-N£Rnberg (Fau)

Curated by ChEMBL
LigandPNGBDBM50407517((-)ISOPROTERENOL | CHEMBL1160723 | US9492405, 27)
Affinity DataEC50:  44nMAssay Description:Agonist activity at beta1-adrenergic receptor (unknown origin) expressed in HEK293T cells harboring GFP/Rluc2-tagged beta-arrestin2 assessed as incre...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1 adrenergic receptor(Homo sapiens (Human))
Friedrich-Alexander University Erlangen-N£Rnberg (Fau)

Curated by ChEMBL
LigandPNGBDBM50407517((-)ISOPROTERENOL | CHEMBL1160723 | US9492405, 27)
Affinity DataEC50:  52nMAssay Description:Agonist activity at beta1-adrenergic receptor (unknown origin) expressed in HEK293T cells harboring GFP/Rluc2-tagged beta-arrestin2 assessed as incre...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1 adrenergic receptor(GUINEA PIG)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50407517((-)ISOPROTERENOL | CHEMBL1160723 | US9492405, 27)
Affinity DataEC50:  2.20nMAssay Description:Activity for Beta-1 adrenergic receptor was assessed from ability to stimulate contractions in isolated guinea pig atrium.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1 adrenergic receptor(Homo sapiens (Human))
Friedrich-Alexander University Erlangen-N£Rnberg (Fau)

Curated by ChEMBL
LigandPNGBDBM50407517((-)ISOPROTERENOL | CHEMBL1160723 | US9492405, 27)
Affinity DataEC50:  50nMAssay Description:Agonist activity at beta1-adrenergic receptor (unknown origin) expressed in HEK293T cells harboring GFP/Rluc2-tagged beta-arrestin2 assessed as incre...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed