Compile Data Set for Download or QSAR
maximum 50k data
Found 6 Enz. Inhib. hit(s) with Target = 'Beta-2 adrenergic receptor' and Ligand = 'BDBM50213121'
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Medical University Of Lublin

Curated by ChEMBL
LigandPNGBDBM50213121((S)-(+)-5-(1-hydroxy-2-phenethylaminoethyl)-1,3-be...)
Affinity DataKi:  2.04E+4nMAssay Description:Displacement of [3H]CGP12177 from human beta-2 adrenergic receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Medical University Of Lublin

Curated by ChEMBL
LigandPNGBDBM50213121((S)-(+)-5-(1-hydroxy-2-phenethylaminoethyl)-1,3-be...)
Affinity DataKi:  2.06E+4nM ΔG°:  -24.9kJ/molepH: 7.8 T: 2°CAssay Description:Beta1-AR binding was done on rat cortical membrane following a previously described procedure (Beer et al., Biochem. Pharmacol. 37: 1145-1151, 1988)....More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Medical University Of Lublin

Curated by ChEMBL
LigandPNGBDBM50213121((S)-(+)-5-(1-hydroxy-2-phenethylaminoethyl)-1,3-be...)
Affinity DataKi:  2.06E+7nMAssay Description:Twenty-four hours after adenoviral infection with human β2-AR, HEK293 cells were harvested in lysis buffer, Tris-HCl [5 mM, pH 7.4] containing E...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Medical University Of Lublin

Curated by ChEMBL
LigandPNGBDBM50213121((S)-(+)-5-(1-hydroxy-2-phenethylaminoethyl)-1,3-be...)
Affinity DataKi:  2.06E+7nMAssay Description:HEK 293 cells stability transfected with cDNA encoding human β2-AR (provided by Dr. Brian Kobilka, Stanford Medical Center, Palo Alto, Calif.) w...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Medical University Of Lublin

Curated by ChEMBL
LigandPNGBDBM50213121((S)-(+)-5-(1-hydroxy-2-phenethylaminoethyl)-1,3-be...)
Affinity DataKd:  2.04E+4nMpH: 7.7Assay Description:HEK 293 cells stability transfected with cDNA encoding human beta2-AR (provided by Dr. Brian Kobilka, Stanford Medical Center, Palo Alto, Calif.) wer...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Medical University Of Lublin

Curated by ChEMBL
LigandPNGBDBM50213121((S)-(+)-5-(1-hydroxy-2-phenethylaminoethyl)-1,3-be...)
Affinity DataKd:  2.04E+4nMAssay Description:HEK 293 cells stability transfected with cDNA encoding human β2-AR (provided by Dr. Brian Kobilka, Stanford Medical Center, Palo Alto, Calif.) w...More data for this Ligand-Target Pair
In DepthDetails US Patent