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Found 1 Enz. Inhib. hit(s) with Target = 'Beta-lactamase TEM' and Ligand = 'BDBM466977'
TargetBeta-lactamase TEM(Escherichia coli)
Entasis Therapeutics

US Patent
LigandPNGBDBM466977(2-[[(2S,5R)-2-(5-carbamoyl-1,3,4-oxadiazol-2-yl)-3...)
Affinity DataIC50:  24nMAssay Description:A buffer consisting of 0.1 M sodium phosphate (pH 7.0), 10 mM NaHCO3, and 0.005% Triton X-100 was used for all enzymes. The chromogenic substrate nit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent