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Found 2 Enz. Inhib. hit(s) with Target = 'Beta-secretase 1' and Ligand = 'BDBM50280525'
TargetBeta-secretase 1(Homo sapiens (Human))
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50280525(CHEMBL4161795)
Affinity DataIC50:  11nMAssay Description:Inhibition of BACE1 (1 to 454 residues) (unknown origin) using APP derived polypeptide harboring Lys-Met/Asn-Leu mutation as substrate by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50280525(CHEMBL4161795)
Affinity DataIC50:  16nMAssay Description:In vitro inhibition of arachidonic acid induced platelet aggregation in human platelet-rich plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed