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Found 2 Enz. Inhib. hit(s) with Target = 'Beta-secretase 1' and Ligand = 'BDBM50545178'
TargetBeta-secretase 1(Homo sapiens (Human))
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50545178(CHEMBL4648883)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of BACE1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50545178(CHEMBL4648883)
Affinity DataIC50:  3.5nMAssay Description:Inhibition of BACE1 (unknown origin) assessed as reduction in Abeta42 level by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed