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Found 1 Enz. Inhib. hit(s) with Target = 'Beta-secretase 1 [22-454]' and Ligand = 'BDBM16287'
TargetBeta-secretase 1 [22-454](Homo sapiens (Human))
Sunesis

LigandPNGBDBM16287(3-N-[(1R,3S,4S)-3-amino-1-{[(1S)-1-(benzylcarbamoy...)
Affinity DataKi:  120nM ΔG°:  -39.1kJ/molepH: 4.5 T: 2°CAssay Description:Compounds were tested for their ability to inhibit BACE-1 hydrolysis of the internally quenched fluorescent substrate FS-2. Reactions were initiated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed