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Found 1 Enz. Inhib. hit(s) with Target = 'Beta-secretase 2' and Ligand = 'BDBM335456'
TargetBeta-secretase 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM335456((3R,6S)-5-amino-3-(5-((7- bromopyrido[3,2-d]pyrimi...)
Affinity DataKi:  0.730nMAssay Description:The compounds of the invention were determined to be potent inhibitors of BACE-2 using the following assay. Inhibitor IC50s at purified human autoBAC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent