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Found 3 Enz. Inhib. hit(s) with Target = 'Beta-secretase 2' and Ligand = 'BDBM338837'
TargetBeta-secretase 2(Homo sapiens (Human))
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM338837(US9751886, Compound 2)
Affinity DataIC50:  5.30nMAssay Description:Inhibition of BACE2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBeta-secretase 2(Homo sapiens (Human))
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM338837(US9751886, Compound 2)
Affinity DataIC50:  5.37nMAssay Description:This assay is a Fluorescence Resonance Energy Transfer Assay (FRET) based assay. The substrate for this assay contains the ¿Swedish¿ Lys-Met/Asn-Leu ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-secretase 2(Homo sapiens (Human))
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM338837(US9751886, Compound 2)
Affinity DataIC50:  5.5nMAssay Description:Inhibition of BACE2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed