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Found 1 Enz. Inhib. hit(s) with Target = 'Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN [517-1238]' and Ligand = 'BDBM646474'
TargetBifunctional 3'-5' exonuclease/ATP-dependent helicase WRN [517-1238](Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM646474(US11878973, Example 58)
Affinity DataIC50:  60nMAssay Description:The core helicase motif of the WRN protein (aa N517-P1238) was produced for this assay (protein production as described above). A 45 oligonucleotide ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent