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Found 1 Enz. Inhib. hit(s) with Target = 'Bifunctional dihydrofolate reductase-thymidylate synthase' and Ligand = 'BDBM18759'
LigandPNGBDBM18759(1,2-naphthalein derivative, 5 | 3,3-bis(3,5-dibrom...)
Affinity DataKi:  4.10E+4nM ΔG°:  -24.6kJ/molepH: 7.0 T: 2°CAssay Description:The inhibition assay pattern for all of the compounds was determined by steady-state kinetic analysis of the dependence of the TS enzyme activity on ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed