Compile Data Set for Download or QSAR
Report error Found 1 Enz. Inhib. hit(s) with Target = 'Bifunctional dihydrofolate reductase-thymidylate synthase [N51I,C59R,S108N,I164L]' and Ligand = 'BDBM18792'
LigandPNGBDBM18792(Chlorazin | 1-(4-chlorophenyl)-6,6-dimethyl-1,6-di...)
Affinity DataKi:  254nM ΔG°:  -37.6kJ/mole IC50: 1.00E+5nMpH: 7.0 T: 2°CAssay Description:The concentration of inhibitor that inhibited 50% of the parasite growth (IC50) was determined from the sigmoidal curve obtained by plotting the perc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2007
Entry Details Article
PubMedPDB3D3D Structure (crystal)