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Found 3 Enz. Inhib. hit(s) with Target = 'Bifunctional epoxide hydrolase 2' and Ligand = 'BDBM50297399'
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50297399(CHEMBL564145 | N-[3-(4-Fluorophenyl)-3-(4-methanes...)
Affinity DataIC50:  8nMAssay Description:Displacement of rhodamine-labeled probe from human soluble epoxide hydrolase by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Rattus norvegicus)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50297399(CHEMBL564145 | N-[3-(4-Fluorophenyl)-3-(4-methanes...)
Affinity DataIC50:  14nMAssay Description:Displacement of rhodamine-labeled probe from rat soluble epoxide hydrolase by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50297399(CHEMBL564145 | N-[3-(4-Fluorophenyl)-3-(4-methanes...)
Affinity DataEC50:  0.600nMAssay Description:Inhibition of human soluble epoxide hydrolase in human HepG cells assessed as conversion of epoxyeicosatienoic acid to dihydroxyeicosatrienoic acid a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed