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Found 3 Enz. Inhib. hit(s) with Target = 'Bifunctional ligase/repressor BirA' and Ligand = 'BDBM161467'
TargetBifunctional ligase/repressor BirA(Staphylococcus aureus)
Monash University

US Patent
LigandPNGBDBM161467(US9108978, 3.25)
Affinity DataKi:  1.83E+3nM ΔG°:  -34.1kJ/mole IC50:  1.16E+4nMpH: 8.0 T: 2°CAssay Description:Quantitation of BPL catalysed 3H-biotin incorporation into the biotin domain substrate was performed as previously described by Polyak et al, J. Biol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBifunctional ligase/repressor BirA(Escherichia coli)
Monash University

US Patent
LigandPNGBDBM161467(US9108978, 3.25)
Affinity DataKi: >3.00E+4nM ΔG°: >-26.9kJ/molepH: 8.0 T: 2°CAssay Description:Quantitation of BPL catalysed 3H-biotin incorporation into the biotin domain substrate was performed as previously described by Polyak et al, J. Biol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBifunctional ligase/repressor BirA(Escherichia coli)
Monash University

US Patent
LigandPNGBDBM161467(US9108978, 3.25)
Affinity DataKi: >3.00E+4nM ΔG°: >-26.9kJ/molepH: 8.0 T: 2°CAssay Description:Quantitation of BPL catalysed 3H-biotin incorporation into the biotin domain substrate was performed as previously described by Polyak et al, J. Biol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent