Found 2 Enz. Inhib. hit(s) with Target = 'Bifunctional purine biosynthesis protein ATIC' and Ligand = 'BDBM24692' TargetBifunctional purine biosynthesis protein ATIC(Homo sapiens (Human))
The Scripps Research Institute
The Scripps Research Institute
Affinity DataKi: 2.00E+4nMAssay Description:Enzyme activity assays of recombinant hGAR Tfase and recombinant hAICAR Tfase were performed as previously described. Kinetics of the enzyme reaction...More data for this Ligand-Target Pair
TargetBifunctional purine biosynthesis protein ATIC(Homo sapiens (Human))
The Scripps Research Institute
The Scripps Research Institute
Affinity DataKi: 2.00E+4nM ΔG°: -26.9kJ/molepH: 7.4 T: 2°CAssay Description:Recombinant human AICAR Tfase was used in the inhibition assay. The reaction was monitored at 298 nm by measuring the increase in absorbance correspo...More data for this Ligand-Target Pair
