Found 10 Enz. Inhib. hit(s) with Target = 'Bromodomain-containing protein 4' and Ligand = 'BDBM188519' 
Affinity DataIC50: 3.20E+3nMAssay Description:Displacement of biotinylated ligand from BRD4 bromodomain-1 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataIC50: 5.85E+3nMAssay Description:Inhibition of human BRD4 by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7.12E+3nMAssay Description:Inhibition of human BRD4 BD1 (67 to 152 residues) preincubated for 15 mins followed by addition of C-terminal biotinylated synthetic K5,8,12,16 tetra...More data for this Ligand-Target Pair
Affinity DataIC50: 7.94E+3nMAssay Description:Inhibition of His-tagged BRD4 BD1 (unknown origin) using biotinylated-JQ1 peptide as substrate incubated for 1 hr by AlphaScreen assayMore data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of biotinylated-H4KAc4 binding to human His6-tagged BRD4 bromodomain-1 (N44 to E168 residues) expressed in Escherichia coli BL21(DE3) afte...More data for this Ligand-Target Pair
Affinity DataIC50: 2.78E+4nMAssay Description:Inhibition of human BRD4 BD1 (67 to 152 residues) preincubated for 15 mins followed by addition of C-terminal biotinylated synthetic K5,8,12,16 tetra...More data for this Ligand-Target Pair
Affinity DataKd: 850nMAssay Description:Binding affinity to human BRD4 bromodomain1 by isothermal titration calorimetryMore data for this Ligand-Target Pair
Affinity DataKd: 5.20E+3nMAssay Description:Binding affinity to human BRD4 bromodomain2 by isothermal titration calorimetryMore data for this Ligand-Target Pair
Affinity DataKd: 850nMAssay Description:Binding affinity to human BRD4 measured at 15 degreeC by ITC assayMore data for this Ligand-Target Pair
Affinity DataKd: 850nMAssay Description:Experiments were performed using recombinant CBP and BRD4 bromodomainsusing the procedure reported recently (Hett et al., 2015).More data for this Ligand-Target Pair
