Compile Data Set for Download or QSAR
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Found 8 Enz. Inhib. hit(s) with Target = 'C-C chemokine receptor type 1' and Ligand = 'BDBM50436256'
TargetC-C chemokine receptor type 1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50436256(CHEMBL2398726)
Affinity DataIC50:  0.800nMAssay Description:Binding affinity to human CCR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50436256(CHEMBL2398726)
Affinity DataIC50:  1nMAssay Description:Antagonist activity at human CCR1 assessed as inhibition of RANTES-induced chemotaxisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50436256(CHEMBL2398726)
Affinity DataIC50:  2.10nMAssay Description:Antagonist activity at human CCR1 assessed as inhibition of MIP1alpha-induced chemotaxisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50436256(CHEMBL2398726)
Affinity DataIC50:  2.70nMAssay Description:Antagonist activity at human CCR1 assessed as inhibition of MPIF-1-induced chemotaxisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50436256(CHEMBL2398726)
Affinity DataIC50:  4nMAssay Description:Antagonist activity at human CCR1 assessed as inhibition of HCC-1-induced chemotaxisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50436256(CHEMBL2398726)
Affinity DataIC50:  4.40nMAssay Description:Antagonist activity at human CCR1 assessed as inhibition of ieukotactin-1-induced chemotaxisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50436256(CHEMBL2398726)
Affinity DataIC50:  46nMAssay Description:Antagonist activity at CCR1 in whole blood (unknown origin) assessed as inhibition of MIP1alpha-induced upregulation of beta2-integrin CD11bMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50436256(CHEMBL2398726)
Affinity DataIC50:  54nMAssay Description:Antagonist activity at CCR1 in whole blood (unknown origin) assessed as inhibition of LKN1-induced upregulation of beta2-integrin CD11bMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed