Compile Data Set for Download or QSAR
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Found 3 Enz. Inhib. hit(s) with Target = 'C-C chemokine receptor type 1' and Ligand = 'BDBM50436259'
TargetC-C chemokine receptor type 1(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM50436259(CHEMBL2398716 | US8633226, 1356)
Affinity DataKi:  3.70nM ΔG°:  -48.1kJ/moleT: 2°CAssay Description:For radioligand competition studies, a final concentration of 1x105 THP-1 monocytic leukemia cells are combined with 100 μg of LS WGA PS beads (...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetC-C chemokine receptor type 1(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM50436259(CHEMBL2398716 | US8633226, 1356)
Affinity DataIC50:  3nMAssay Description:Displacement of [125I]MIP-1alpha from CCR1 in human THP1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 1(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM50436259(CHEMBL2398716 | US8633226, 1356)
Affinity DataIC50:  5.20nMAssay Description:Binding affinity to human CCR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed