Found 3 Enz. Inhib. hit(s) with Target = 'C-C chemokine receptor type 1' and Ligand = 'BDBM50436284'
Affinity DataKi: 0.700nM ΔG°: -52.3kJ/moleT: 2°CAssay Description:For radioligand competition studies, a final concentration of 1x105 THP-1 monocytic leukemia cells are combined with 100 μg of LS WGA PS beads (...More data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMAssay Description:Binding affinity to human CCR1More data for this Ligand-Target Pair
Affinity DataIC50: 2.5nMAssay Description:Antagonist activity at human CCR1 assessed as inhibition of MIP1alpha-induced chemotaxisMore data for this Ligand-Target Pair