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Found 9 Enz. Inhib. hit(s) with Target = 'C-C chemokine receptor type 2' and Ligand = 'BDBM50382932'
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50382932(CHEMBL2029422)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of CCR2-mediated Erk phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50382932(CHEMBL2029422)
Affinity DataIC50:  2.80nMAssay Description:Antagonist activity at rat CCR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50382932(CHEMBL2029422)
Affinity DataIC50:  3.30nMAssay Description:Inhibition of CCR2-mediated calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50382932(CHEMBL2029422)
Affinity DataIC50:  3.90nMAssay Description:Antagonist activity at CCR2 receptor in human PBMC assessed as inhibition of MCP1-mediated leukocyte chemotaxis after 30 mins by microscopyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50382932(CHEMBL2029422)
Affinity DataIC50:  5.20nMAssay Description:Displacement of [125I]MCP1 from human CCR2 in PBMC after 30 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50382932(CHEMBL2029422)
Affinity DataIC50:  13nMAssay Description:Binding affinity to rat CCR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50382932(CHEMBL2029422)
Affinity DataIC50:  16nMAssay Description:Antagonist activity at mouse CCR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50382932(CHEMBL2029422)
Affinity DataIC50:  17nMAssay Description:Binding affinity to mouse CCR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50382932(CHEMBL2029422)
Affinity DataIC50:  19nMAssay Description:Antagonist activity at CCR2 receptor in human whole blood assessed as inhibition of alexa-tagged MCP-induced effect 30 mins by flow cytometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed