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Found 3 Enz. Inhib. hit(s) with Target = 'C-C chemokine receptor type 4' and Ligand = 'BDBM50198429'
TargetC-C chemokine receptor type 4(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50198429((S)-(4-(4-(2,4-dichlorobenzylamino)pyrido[2,3-d]py...)
Affinity DataIC50:  3nMAssay Description:Antagonist activity at human CCR4 expressed in CEMS529 cells assessed as effect on calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 4(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50198429((S)-(4-(4-(2,4-dichlorobenzylamino)pyrido[2,3-d]py...)
Affinity DataIC50:  7nMAssay Description:Inhibition of MDC-induced chemotaxis in L1.2 cells expressing CCR4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 4(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50198429((S)-(4-(4-(2,4-dichlorobenzylamino)pyrido[2,3-d]py...)
Affinity DataIC50:  20nMAssay Description:Displacement of [125I]MDC from human CCR4 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed