Compile Data Set for Download or QSAR
maximum 50k data
Found 2 Enz. Inhib. hit(s) with Target = 'C-X-C chemokine receptor type 2' and Ligand = 'BDBM420280'
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Syntrix Biosystems

US Patent
LigandPNGBDBM420280(SX-627 | USRE47740, Compound 7 | USRE48547, Compou...)
Affinity DataIC50:  1.50E+3nMAssay Description:An in vitro assay showed inhibition of CXCR2-mediated intracellular calcium release by treatment with compound 9 (IC50=586±91 nM). Briefly, human neu...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Syntrix Biosystems

US Patent
LigandPNGBDBM420280(SX-627 | USRE47740, Compound 7 | USRE48547, Compou...)
Affinity DataIC50:  1.50E+3nMAssay Description:Briefly, human neutrophils were suspended in HBSS− (without Ca2+ and Mg2+) containing 10 mM HEPES and FLIPR Calcium 3 dye (3.1×107 cells in tot...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent