Found 5 Enz. Inhib. hit(s) with Target = 'C-X-C chemokine receptor type 6' and Ligand = 'BDBM50539483' TargetC-X-C chemokine receptor type 6(Homo sapiens)
Sanford Burnham Prebys Medical Discovery Institute
Curated by ChEMBL
Sanford Burnham Prebys Medical Discovery Institute
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Antagonist activity at Prolink-tagged human CXCR6 receptor assessed as inhibition of CXCL16-induced beta-arrestin recruitment by DiscoveRx cell based...More data for this Ligand-Target Pair
TargetC-X-C chemokine receptor type 6(Homo sapiens)
Sanford Burnham Prebys Medical Discovery Institute
Curated by ChEMBL
Sanford Burnham Prebys Medical Discovery Institute
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Antagonist activity at Prolink-tagged human CXCR6 receptor assessed as inhibition of CXCL16-induced beta-arrestin recruitment by DiscoveRx cell based...More data for this Ligand-Target Pair
TargetC-X-C chemokine receptor type 6(Homo sapiens)
Sanford Burnham Prebys Medical Discovery Institute
Curated by ChEMBL
Sanford Burnham Prebys Medical Discovery Institute
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Antagonist activity at Prolink-tagged human CXCR6 receptor assessed as inhibition of forskolin-induced cAMP accumulation by DiscoveRx cell based assa...More data for this Ligand-Target Pair
TargetC-X-C chemokine receptor type 6(Homo sapiens)
Sanford Burnham Prebys Medical Discovery Institute
Curated by ChEMBL
Sanford Burnham Prebys Medical Discovery Institute
Curated by ChEMBL
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of CXCR6-mediated cell invasion in human SKHEP1 cells after 72 hrs by transwell assayMore data for this Ligand-Target Pair
TargetC-X-C chemokine receptor type 6(Mus musculus)
Sanford Burnham Prebys Medical Discovery Institute
Curated by ChEMBL
Sanford Burnham Prebys Medical Discovery Institute
Curated by ChEMBL
Affinity DataIC50: >4.00E+4nMAssay Description:Antagonist activity at mouse CXCR6 by DiscoveRx cell based beta-arrestin assayMore data for this Ligand-Target Pair
