Found 4 Enz. Inhib. hit(s) with Target = 'C5a anaphylatoxin chemotactic receptor 1' and Ligand = 'BDBM50012295'
TargetC5a anaphylatoxin chemotactic receptor 1(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: 3.00E+5nMAssay Description:Inhibition of [125I]-C5a binding to C5a anaphylatoxin chemotactic receptor in PMNL membranesMore data for this Ligand-Target Pair
TargetC5a anaphylatoxin chemotactic receptor 1(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: >1.00E+6nMAssay Description:50% reduction in binding of [125I]-C5a to human polymorphonuclear cells (PMNs)More data for this Ligand-Target Pair
TargetC5a anaphylatoxin chemotactic receptor 1(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataEC50: 1.30nMAssay Description:Abilitiy to induce shape change (polarization) in human polymorphonuclear leukocytes (PMN)More data for this Ligand-Target Pair
TargetC5a anaphylatoxin chemotactic receptor 1(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataEC50: 12nMAssay Description:Release of beta-glucuronidase from human polymorphonuclear leukocytes(PMN)More data for this Ligand-Target Pair