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Found 2 Enz. Inhib. hit(s) with Target = 'Calcium/calmodulin-dependent protein kinase kinase 2' and Ligand = 'BDBM50271737'
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50271737(CHEMBL4128950)
Affinity DataIC50:  126nMAssay Description:Inhibition of full-length human GST-tagged CAMKK2 using 5FAM-AKPKGNKDYHLQTCCGSLAYRRR-amide as substrate preincubated for 30 mins followed by substrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Mus musculus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50271737(CHEMBL4128950)
Affinity DataIC50:  3.98E+3nMAssay Description:Inhibition of CAMKK2 in mouse N39 cells assessed as decrease in AMPKalpha phosphorylation at T172 preincubated for 80 mins followed by inomycin addit...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed