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Found 4 Enz. Inhib. hit(s) with Target = 'Calpain-1 catalytic subunit' and Ligand = 'BDBM50114340'
TargetCalpain-1 catalytic subunit(Rattus norvegicus)
University Of Canterbury

Curated by ChEMBL
LigandPNGBDBM50114340((S)-2-(4-Fluoro-benzenesulfonylamino)-N-((S)-1-for...)
Affinity DataIC50:  7.5nMAssay Description:Inhibition of rat CAPN1 using BODIPY-labeled casein substrate by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Texas A&M University

Curated by ChEMBL
LigandPNGBDBM50114340((S)-2-(4-Fluoro-benzenesulfonylamino)-N-((S)-1-for...)
Affinity DataIC50:  22nMAssay Description:Inhibition of human Calpain-1 incubated for 60 mins by Bio-Rad protein assay dye reagent based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Texas A&M University

Curated by ChEMBL
LigandPNGBDBM50114340((S)-2-(4-Fluoro-benzenesulfonylamino)-N-((S)-1-for...)
Affinity DataIC50:  22nMAssay Description:Inhibition of human erythrocyte mu calpainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Sus scrofa (pig))
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50114340((S)-2-(4-Fluoro-benzenesulfonylamino)-N-((S)-1-for...)
Affinity DataIC50:  35nMAssay Description:Tested for inhibitory activity against porcine erythrocyte Mu-calpainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed