Found 255 Enz. Inhib. hit(s) with Target = 'Carbonic anhydrase 12' and Ligand = 'BDBM10880' 
Affinity DataKi: 2.5nMAssay Description:Inhibition of human carbonic anhydrase 12 assessed as reduction in CO2 hydration preincubated for 15 mins to 2 hrs by phenol red dye based stopped fl...More data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataKi: 2.5nMAssay Description:Inhibition of tumor-associated transmembrane human carbonic anhydrase-12 after 15 mins by Stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Inhibition of human recombinant carbonic anhydrase 12 catalytic domain preincubated for 15 mins by CO2 hydration methodMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Inhibition of carbonic anhydrase 12 (unknown origin) preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 4.80nMAssay Description:Inhibition of human CAH12 expressed in Escherichia coli BL21 (DE3) by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Inhibition of human recombinant transmembrane CA12 catalytic domain after 6 hrs by stopped-flow CO2 hydration methodMore data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Binding affinity to human recombinant CA12 assessed as inhibition constant incubated for 15 mins prior to testing by phenol red based stopped-flow CO...More data for this Ligand-Target Pair
Affinity DataKi: 5.60nMAssay Description:Inhibition of recombinant human carbonic anhydrase-12 assessed as reduction in CO2 hydration preincubated for 10 mins measured for 5 to 10 secs by st...More data for this Ligand-Target Pair
Affinity DataKi: 5.60nMAssay Description:Inhibition of human CA12 after 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 5.60nMAssay Description:Inhibition of recombinant human carbonic anhydrase 12 preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 5.60nMAssay Description:Inhibition of recombinant human catalytic domain of carbonic anhydrase-12 preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 5.60nMAssay Description:Inhibition of human recombinant carbonic anhydrase 12 preincubated for 10 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
Affinity DataKi: 5.60nMAssay Description:Inhibition of human carbonic anhydrase 12 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 5.60nMAssay Description:Inhibition of recombinant human carbonic anhydrase 12 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 5.60nMAssay Description:Inhibition of human CA12 incubated for 15 mins by stopped- flow CO2 hydrase assay methodMore data for this Ligand-Target Pair
Affinity DataKi: 5.60nMAssay Description:Inhibition of human CA12 preincubated for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 5.60nMAssay Description:Inhibition of human recombinant carbonic anhydrase 12 preincubated for 15 mins prior to testing measured for 10 to 100 secs by phenol red-based stopp...More data for this Ligand-Target Pair
Affinity DataKi: 5.60nMAssay Description:Inhibition of recombinant human Carbonic anhydrase 12 assessed as reduction in CO2 hydration preincubated for 15 mins prior to testing measured for 1...More data for this Ligand-Target Pair
Affinity DataKi: 5.60nMAssay Description:Inhibition of recombinant human carbonic anhydrase 12 preincubated for 15 mins prior to testing by phenol red based stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 5.60nMAssay Description:Inhibition of human recombinant transmembrane tumor associated carbonic anhydrase 12 preincubated for 10 mins prior to testing by stopped-flow CO2 hy...More data for this Ligand-Target Pair
Affinity DataKi: 5.60nMAssay Description:Inhibition of human recombinant carbonic anhydrase-12-mediated CO2 hydration preincubated for 10 mins by stopped-flow assayMore data for this Ligand-Target Pair
Affinity DataKi: 5.60nMAssay Description:Inhibition of human carbonic anhydrase 12 for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 5.60nMAssay Description:Inhibition of human recombinant CA12 catalytic domain by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 5.60nMAssay Description:Inhibition of human carbonic anhydrase 12 preincubated for 15 mins by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
Affinity DataKi: 5.70nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
Affinity DataKi: 5.70nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
Affinity DataKi: 5.70nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
Affinity DataKi: 5.70nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
Affinity DataKi: 5.70nMAssay Description:Inhibition assay using carbonic anhydrases.More data for this Ligand-Target Pair
Affinity DataKi: 5.70nMAssay Description:CA-catalyzed CO2 hydration activity methods were published previously by Cornelio et al. as part of a larger series of benzenesulfonamide-based inhib...More data for this Ligand-Target Pair
Affinity DataKi: 5.70nM ΔG°: -43.7kJ/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity. Phenol red (at a concentration of...More data for this Ligand-Target Pair
Affinity DataKi: 5.70nMAssay Description:Inhibition of recombinant human CA12 transmembrane isoform preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 5.70nMAssay Description:Inhibition of human recombinant transmembrane tumor associated carbonic anhydrase-12 incubated for 15 mins prior to testing by stopped-flow CO2 hydra...More data for this Ligand-Target Pair
Affinity DataKi: 5.70nMAssay Description:Inhibition of human cloned transmembrane tumor-associated catalytic domain of carbonic anhydrase 12 preincubated for 15 mins by stopped flow CO2 hydr...More data for this Ligand-Target Pair
Affinity DataKi: 5.70nMAssay Description:Inhibition of human recombinant carbonic anhydrase 12 preincubated for 15 mins by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 5.70nMAssay Description:Inhibition of human recombinant carbonic anhydrase 12 preincubated for 15 mins by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 5.70nMAssay Description:Inhibition of human CA-12 after 15 mins by stopped-flow CO2 hydration methodMore data for this Ligand-Target Pair
Affinity DataKi: 5.70nMAssay Description:Inhibition of human CA-12 by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 5.70nMAssay Description:Inhibition of human recombinant carbonic anhydrase 12 preincubated for 15 mins by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
Affinity DataKi: 5.70nMAssay Description:Inhibition of human carbonic anhydrase 12 by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 5.70nMAssay Description:Inhibition of human carbonic anhydrase 12 by stopped flow CO2 hydrase assay methodMore data for this Ligand-Target Pair
Affinity DataKi: 5.70nMAssay Description:Inhibition of human recombinant carbonic anhydrase 12 pre-incubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 5.70nMAssay Description:Inhibition of recombinant human carbonic anhydrase 12 after 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 5.70nMAssay Description:Inhibition of human recombinant carbonic anhydrase 12 by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
Affinity DataKi: 5.70nMAssay Description:Inhibition of recombinant human carbonic anhydrase 12 preincubated for 15 mins by stopped-flow CO2 hydrase AssayMore data for this Ligand-Target Pair
Affinity DataKi: 5.70nMAssay Description:Inhibition of human tumor-associated carbonic anhydrase 12 by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 5.70nMAssay Description:Inhibition of human recombinant CA-12 after 15 mins by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 5.70nMAssay Description:Inhibition of human recombinant carbonic anhydrase 12 expressed in Escherichia coli pre-incubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 5.70nMAssay Description:Inhibition constant against human carbonic anhydrase XIIMore data for this Ligand-Target Pair
Affinity DataKi: 5.70nMAssay Description:Inhibition of human membrane associated form of carbonic anhydrase-12 assessed as CO2 hydration activity incubated for 15 mins prior to testing by st...More data for this Ligand-Target Pair
