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Found 3 Enz. Inhib. hit(s) with Target = 'Carbonic anhydrase 12' and Ligand = 'BDBM50329823'
TargetCarbonic anhydrase 12(Homo sapiens (Human))
Vilnius University

LigandPNGBDBM50329823(2-Chloro-5-[(2-ethyl-1H-benzimidazol-1-yl)acetyl]b...)
Affinity DataKd:  1.82E+3nMpH: 7.0Assay Description:The thermal shift assay (TSA) measurements were performed in a Corbett Rotor-Gene 6000 (QIAGEN Rotor-Gene Q, Sydney, Australia) instrument using the ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 12(Homo sapiens (Human))
Vilnius University

LigandPNGBDBM50329823(2-Chloro-5-[(2-ethyl-1H-benzimidazol-1-yl)acetyl]b...)
Affinity DataKd:  11nMAssay Description:Binding affinity to recombinant human carbonic anhydrase 12 (1 to 260 residues) expressed in Escherichia coli BL21 (DE3) assessed as intrinsic dissoc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 12(Homo sapiens (Human))
Vilnius University

LigandPNGBDBM50329823(2-Chloro-5-[(2-ethyl-1H-benzimidazol-1-yl)acetyl]b...)
Affinity DataKd:  1.82E+3nMAssay Description:Binding affinity to recombinant human carbonic anhydrase 12 (1 to 260 residues) expressed in Escherichia coli BL21 (DE3) in presence of ANS by fluore...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed