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Found 6 Enz. Inhib. hit(s) with Target = 'Carbonic anhydrase 9' and Ligand = 'BDBM50163863'
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50163863(4-(1H-benzimidazol-1-ylacetyl)-2-chlorobenzenesulf...)
Affinity DataKoff:  3.10E+6s-1Assay Description:Binding affinity to human recombinant CA9 catalytic domain assessed as association rate constant after 30 secs by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50163863(4-(1H-benzimidazol-1-ylacetyl)-2-chlorobenzenesulf...)
Affinity DataKon:  0.140M-1s-1Assay Description:Binding affinity to human recombinant CA9 catalytic domain assessed as dissociation rate constant after 30 secs by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50163863(4-(1H-benzimidazol-1-ylacetyl)-2-chlorobenzenesulf...)
Affinity DataKon:  1.40M-1s-1Assay Description:Binding affinity to human CA9 catalytic domain expressed in mammalian expression system assessed as dissociation rate constant at pH 7 by SPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50163863(4-(1H-benzimidazol-1-ylacetyl)-2-chlorobenzenesulf...)
Affinity DataKd:  20nMAssay Description:Binding affinity to human recombinant CA9 catalytic domain by fluorescence-based thermal shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50163863(4-(1H-benzimidazol-1-ylacetyl)-2-chlorobenzenesulf...)
Affinity DataKd:  0.600nMAssay Description:Binding affinity to human CA9 catalytic domain expressed in mammalian expression system assessed as intrinsic thermodynamic equilibrium constant at p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50163863(4-(1H-benzimidazol-1-ylacetyl)-2-chlorobenzenesulf...)
Affinity DataKd:  47nMAssay Description:Binding affinity to human recombinant CA9 catalytic domain after 30 secs by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed