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Found 1 Enz. Inhib. hit(s) with Target = 'Caspase-1' and Ligand = 'BDBM12064'
TargetCaspase-1(Homo sapiens (Human))
Pfizer

LigandPNGBDBM12064((3S)-3-({2-[3-methyl-4-(propan-2-yl)phenoxy]benzen...)
Affinity DataKi:  110nM ΔG°:  -41.3kJ/molepH: 7.0 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors, and the accumulation of AMC was assessed with a Cytof...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed