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Found 3 Enz. Inhib. hit(s) with Target = 'Caspase-7' and Ligand = 'BDBM160786'
TargetCaspase-7(Homo sapiens (Human))
Novagenesis Foundation

US Patent
LigandPNGBDBM160786(US10167313, Compound 53 | US9045524, 53)
Affinity DataIC50:  800nMAssay Description:The inhibition of the activity of Caspase-1 to -10 by four different compounds (#53, #111, #123 & Z-DEVD-FMK used as a prodrug: z-D(OMe)E(OMe)VD(OMe)...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCaspase-7(Homo sapiens (Human))
Novagenesis Foundation

US Patent
LigandPNGBDBM160786(US10167313, Compound 53 | US9045524, 53)
Affinity DataIC50:  800nMAssay Description:Selectivity of compound 55, compound 63, compound 48, compound 57, compound 88 toward caspase-1 (pro-inflammatory group), caspase-5 (group I), caspas...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCaspase-7(Homo sapiens (Human))
Novagenesis Foundation

US Patent
LigandPNGBDBM160786(US10167313, Compound 53 | US9045524, 53)
Affinity DataIC50:  800nMT: 2°CAssay Description:Selectivity of compound 55, compound 63, compound 48, compound 57, compound 88 toward caspase-1 (pro-inflammatory group), caspase-5 (group I), caspas...More data for this Ligand-Target Pair
In DepthDetails US Patent