BindingDB PrimarySearch

Found 2 Enz. Inhib. hit(s) with Target = 'Catechol O-methyltransferase' and Ligand = 'BDBM50086214'

Catechol O-methyltransferase(Rattus norvegicus (Rat))
Merck Research Laboratories

Curated by ChEMBL

IC50: 19nMAssay Description:Inhibition of recombinant rat membrane bound COMT expressed in Escherichia coli BL21-CodonPlus(DE3)-RIPL using dopamine/SAM as substrate/cofactor pre...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid PDB Similars

Details Article PubMed

Catechol O-methyltransferase(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL

BDBM50086214(CHEMBL3425744)

IC50: 200nMAssay Description:Inhibition of C-terminal His6-tagged recombinant human membrane bound COMT expressed in Bacmid infected Sf-9 insect cells using dopamine/SAM as subst...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid PDB Similars

Details Article PubMed PDB

3D Structure (crystal)