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Found 3 Enz. Inhib. hit(s) with Target = 'Coagulation factor IX' and Ligand = 'BDBM241441'
TargetCoagulation factor IX(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM241441(US9409908, 177 | US9409908, 178 | US9409908, 73 | ...)
Affinity DataKi:  0.800nMpH: 7.4Assay Description:Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor IX(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM241441(US9409908, 177 | US9409908, 178 | US9409908, 73 | ...)
Affinity DataKi:  0.880nMpH: 7.4Assay Description:Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor IX(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM241441(US9409908, 177 | US9409908, 178 | US9409908, 73 | ...)
Affinity DataKi:  0.920nMpH: 7.4Assay Description:Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent