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Found 1 Enz. Inhib. hit(s) with Target = 'Coagulation factor XI' and Ligand = 'BDBM619957'
TargetCoagulation factor XI(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM619957(6-(2-((3S,8aR)-7-(3-Chloro-2-fluoro-6-(1H-tetrazol...)
Affinity DataIC50:  0.300nMAssay Description:A fluorescence intensity (FLINT) based assay was used to monitor inhibition of Factor XIa. The peptide substrate, 5Fam-KLTRAETV-K5Tamra (purchased fr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent