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Found
1
Enz. Inhib. hit(s) with Target = 'Coagulation factor XI' and Ligand = 'BDBM619957'
Target
Coagulation factor XI
(Homo sapiens (Human))
Janssen Pharmaceutica
US Patent
Ligand
BDBM619957
(6-(2-((3S,8aR)-7-(3-Chloro-2-fluoro-6-(1H-tetrazol...)
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Affinity Data
IC50: 0.300nM
Assay Description:
A fluorescence intensity (FLINT) based assay was used to monitor inhibition of Factor XIa. The peptide substrate, 5Fam-KLTRAETV-K5Tamra (purchased fr...
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Target Info
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Ligand Info
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US Patent
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