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Found 4 Enz. Inhib. hit(s) with Target = 'Complement factor B' and Ligand = 'BDBM159545'
TargetComplement factor B(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM159545(US10093663, Example 17-30 | US9682968, Example-17-...)
Affinity DataIC50:  0.0100nMAssay Description:CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetComplement factor B(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM159545(US10093663, Example 17-30 | US9682968, Example-17-...)
Affinity DataIC50:  0.0200nMAssay Description:CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetComplement factor B(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM159545(US10093663, Example 17-30 | US9682968, Example-17-...)
Affinity DataIC50:  13nMpH: 7.4 T: 2°CAssay Description:CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetComplement factor B(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM159545(US10093663, Example 17-30 | US9682968, Example-17-...)
Affinity DataIC50:  23nMpH: 7.4 T: 2°CAssay Description:CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent