Compile Data Set for Download or QSAR
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Found 2 Enz. Inhib. hit(s) with Target = 'Complement factor D' and Ligand = 'BDBM50238246'
TargetComplement factor D(Homo sapiens (Human))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50238246(CHEMBL4098439)
Affinity DataIC50:  14nMAssay Description:Inhibition of recombinant human complement factor D catalytic domain using Z-Lys-thiobenzylester as substrate preincubated for 1 hr followed by subst...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement factor D(Homo sapiens (Human))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50238246(CHEMBL4098439)
Affinity DataIC50:  22nMAssay Description:Inhibition of complement factor D in human whole blood assessed as decrease in zymosan-induced AP activation mediated soluble MAC complex formation p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed