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Found 2 Enz. Inhib. hit(s) with Target = 'Cyclic GMP-AMP synthase' and Ligand = 'BDBM50015214'
TargetCyclic GMP-AMP synthase(Homo sapiens)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50015214(6-chloro-2-methoxy-9-acridinyl(4-diethylamino-1-me...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of cGAS in human THP-1 cellsMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCyclic GMP-AMP synthase(Homo sapiens)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50015214(6-chloro-2-methoxy-9-acridinyl(4-diethylamino-1-me...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of cGAS (unknown origin) incubated for 1 hr by Typhoon imaging system analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed