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Found 1 Enz. Inhib. hit(s) with Target = 'Cyclic GMP-AMP synthase' and Ligand = 'BDBM639870'
TargetCyclic GMP-AMP synthase(Homo sapiens)
Eli Lilly

US Patent
LigandPNGBDBM639870(6,7-Dichloro-9-(3-hydroxypropoxy)-2-methyl-10-(1H-...)
Affinity DataIC50:  7.89nMAssay Description:In vitro inhibition assay of cGAS activity: Add a 5 μL mixture containing 10 mM Tris-Cl pH 7.5, 50 mM NaCl, 5 mM MgCl2, 1 mM DTT, 0.01% Triton X...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent