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Found 2 Enz. Inhib. hit(s) with Target = 'Cyclic GMP-AMP synthase [155-522]' and Ligand = 'BDBM457217'
TargetCyclic GMP-AMP synthase [155-522](Homo sapiens (Human))
Aduro Biotech

US Patent
LigandPNGBDBM457217(US10738056, Compound A1085 | US10738056, Compound ...)
Affinity DataIC50: <20nMAssay Description:Protein was expressed and purified from E. coli BL21 DE3 Rosetta 2 (EMD Millipore) cells using standard techniques. Cells were grown in 2x yeast extr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclic GMP-AMP synthase [155-522](Homo sapiens (Human))
Aduro Biotech

US Patent
LigandPNGBDBM457217(US10738056, Compound A1085 | US10738056, Compound ...)
Affinity DataIC50:  135nMAssay Description:Protein was expressed and purified from E. coli BL21 DE3 Rosetta 2 (EMD Millipore) cells using standard techniques. Cells were grown in 2x yeast extr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent